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@pirl-unc

Personalized Immunotherapy Research Lab @ UNC

Collective of researchers at UNC-CH who combine experimental and computational approaches to develop new immunotherapies and bring them into the clinic.
README.md

PIRL

The Personalilized Immunotherapy Research Lab (PIRL) is a multi-PI research group at the University of North Carolina - Chapel Hill. We work on identifying the determinants immune-mediated tumor clearance in a way that's fully personalized to each individual and their cancer. That high degree of personalization is manifested in algorithms for antigen identification across the spheres of genomics, proteomics, and machine learning for immunology.

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  1. mhcgnomes mhcgnomes Public

    Parsing MHC nomenclature in the wild

    Python 16 3

  2. ace ace Public

    Jupyter Notebook 2 1

  3. defense-against-the-dark-arts defense-against-the-dark-arts Public

    Course website and resources for BCB 731

    HTML

  4. golfy golfy Public

    Heuristic solver for pooled peptide experiment design

    Jupyter Notebook 1

  5. lens lens Public

    Landscape of Effective Neoantigens Software

  6. are-we-good are-we-good Public

    CI status of every project we develop and/or help maintain

Repositories

Showing 10 of 80 repositories
  • PRAME_in_NUT_Carcinoma Public
    pirl-unc/PRAME_in_NUT_Carcinoma’s past year of commit activity
    R 0 MIT 0 0 0 Updated Apr 2, 2025
  • rserver-binfotron Public
    pirl-unc/rserver-binfotron’s past year of commit activity
    Dockerfile 0 Apache-2.0 1 2 0 Updated Apr 1, 2025
  • housekeeping Public
    pirl-unc/housekeeping’s past year of commit activity
    R 0 Apache-2.0 0 0 0 Updated Apr 1, 2025
  • binfotron Public
    pirl-unc/binfotron’s past year of commit activity
    R 1 Apache-2.0 1 2 0 Updated Apr 1, 2025
  • datasetprep Public

    Methods to make life easier when preparing datasets for analysis.

    pirl-unc/datasetprep’s past year of commit activity
    R 0 Apache-2.0 0 1 0 Updated Apr 1, 2025
  • translate-pacbio-reads-for-bbn963 Public
    pirl-unc/translate-pacbio-reads-for-bbn963’s past year of commit activity
    Jupyter Notebook 0 Apache-2.0 0 0 0 Updated Mar 26, 2025
  • longread-fusion-transcript-pipeline Public
    pirl-unc/longread-fusion-transcript-pipeline’s past year of commit activity
    R 0 0 0 0 Updated Mar 24, 2025
  • mhcgnomes Public

    Parsing MHC nomenclature in the wild

    pirl-unc/mhcgnomes’s past year of commit activity
    Python 16 Apache-2.0 3 11 0 Updated Mar 24, 2025
  • lineardesign Public

    docker image to run externally developed LinearDesign software

    pirl-unc/lineardesign’s past year of commit activity
    0 GPL-3.0 0 0 0 Updated Feb 28, 2025
  • MiXCR Public

    Dockerfile and script to run MiXCR

    pirl-unc/MiXCR’s past year of commit activity
    Dockerfile 0 Apache-2.0 0 0 0 Updated Feb 25, 2025
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